{"id":70040,"date":"2021-07-13T12:33:44","date_gmt":"2021-07-13T03:33:44","guid":{"rendered":"http:\/\/mackenmov.sunnyday.jp\/wordpress\/?p=70040"},"modified":"2021-07-13T12:45:27","modified_gmt":"2021-07-13T03:45:27","slug":"%e3%80%90%e8%ab%96%e6%96%87%e3%80%91sars-cov-2%e3%81%ae%e4%ba%88%e9%98%b2%e6%8e%a5%e7%a8%ae%e3%82%92%e5%8f%97%e3%81%91%e3%81%9f%e6%82%a3%e8%80%85%e3%81%ab%e6%ad%bb%e5%be%8c%e8%aa%bf%e6%9f%bb%e3%82%92","status":"publish","type":"post","link":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/archives\/70040","title":{"rendered":"\u3010\u8ad6\u6587\u3011SARS-CoV-2\u306e\u4e88\u9632\u63a5\u7a2e\u3092\u53d7\u3051\u305f\u60a3\u8005\u306b\u6b7b\u5f8c\u8abf\u67fb\u3092\u884c\u3063\u305f\u521d\u3081\u3066\u306e\u30b1\u30fc\u30b9"},"content":{"rendered":"<p>First case of postmortem study in a patient vaccinated against SARS-CoV-2<\/p>\n<p>\u3068\u3044\u3046\u8ad6\u6587\u304c\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002\u2193<\/p>\n<p>International Journal of Infectious Diseases<br \/>\nVolume 107, June 2021, Pages 172-175<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1201971221003647\" target=\"_blank\" rel=\"noopener\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1201971221003647<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>SARS-CoV-2\u306e\u4e88\u9632\u63a5\u7a2e\u3092\u53d7\u3051\u305f\u60a3\u8005\u306b\u6b7b\u5f8c\u8abf\u67fb\u3092\u884c\u3063\u305f\u521d\u3081\u3066\u306e\u30b1\u30fc\u30b9<\/p>\n<p>\u8981\u7d04<\/p>\n<p>\u3053\u308c\u307e\u3067\u75c7\u72b6\u306e\u306a\u304b\u3063\u305f86\u6b73\u306e\u7537\u6027\u304c\uff0cBNT162b2 mRNA COVID-19\u30ef\u30af\u30c1\u30f3\u306e\u521d\u56de\u63a5\u7a2e\u3092\u53d7\u3051\u305f\uff0e<\/p>\n<p>\u305d\u306e4\u9031\u9593\u5f8c\u306b\u6025\u6027\u814e\u4e0d\u5168\u3068\u547c\u5438\u4e0d\u5168\u3067\u6b7b\u4ea1\u3057\u305f\uff0e<\/p>\n<p>COVID-19\u7279\u6709\u306e\u75c7\u72b6\u306f\u898b\u3089\u308c\u306a\u304b\u3063\u305f\u304c\uff0c\u751f\u524d\u306bSARS-CoV-2\u306e\u967d\u6027\u53cd\u5fdc\u304c\u51fa\u3066\u3044\u305f\uff0e<\/p>\n<p>\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\uff08S1\uff09\u306e\u6297\u539f\u7d50\u5408\u3067\u306f\u3001\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\uff08Ig\uff09G\u304c\u6709\u610f\u306b\u9ad8\u304b\u3063\u305f\u304c\u3001\u30cc\u30af\u30ec\u30aa\u30ad\u30e3\u30d7\u30b7\u30c9IgG\/IgM\u306f\u8a98\u767a\u3055\u308c\u306a\u304b\u3063\u305f\u3002<\/p>\n<p>\u5256\u691c\u3067\u306f\u3001\u6025\u6027\u6c17\u7ba1\u652f\u80ba\u708e\u3068\u5c3f\u7d30\u7ba1\u4e0d\u5168\u304c\u6b7b\u56e0\u3068\u3055\u308c\u305f\u304c\u3001COVID-19\u306b\u7279\u5fb4\u7684\u306a\u5f62\u614b\u5b66\u7684\u7279\u5fb4\u306f\u89b3\u5bdf\u3055\u308c\u306a\u304b\u3063\u305f\u3002<\/p>\n<p>\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u9023\u9396\u53cd\u5fdc\u306b\u3088\u308b\u6b7b\u5f8c\u306e\u5206\u5b50\u30de\u30c3\u30d4\u30f3\u30b0\u3067\u306f\uff0c<span style=\"color: #ff0000;\">\u809d\u81d3\u3068\u55c5\u7403\u3092\u9664\u304f\u3059\u3079\u3066\u306e\u81d3\u5668\uff08\u53e3\u8154\u54bd\u982d\uff0c\u55c5\u899a\u7c98\u819c\uff0c\u6c17\u7ba1\uff0c\u80ba\uff0c\u5fc3\u81d3\uff0c\u814e\u81d3\uff0c\u5927\u8133\uff09\u3067\uff0c\u95a2\u9023\u3059\u308bSARS-CoV-2\u30b5\u30a4\u30af\u30eb\u95be\u5024\u304c\u691c\u51fa\u3055\u308c\u305f\u3002<\/span><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-70041\" src=\"https:\/\/i0.wp.com\/mackenmov.sunnyday.jp\/wordpress\/wp-content\/uploads\/2021\/07\/vac.jpg?resize=600%2C627\" alt=\"spread spike protein\" width=\"600\" height=\"627\" data-recalc-dims=\"1\" \/><\/p>\n<h3>\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u30011\u56de\u76ee\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u3088\u3063\u3066\u3001<span style=\"color: #ff0000;\">\u514d\u75ab\u539f\u6027\u306f\u8a98\u5c0e\u3055\u308c\u308b\u304c\u3001\u7121\u83cc\u514d\u75ab\u306f\u8a98\u5c0e\u3055\u308c\u306a\u3044\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3002<\/span><\/h3>\n<p>www.DeepL.com\/Translator\uff08\u7121\u6599\u7248\uff09\u3067\u7ffb\u8a33\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\u539f\u6587<\/p>\n<p>Abstract<\/p>\n<p>A previously symptomless 86-year-old man received the first dose of the BNT162b2 mRNA COVID-19 vaccine. He died 4 weeks later from acute renal and respiratory failure.<\/p>\n<p>Although he did not present with any COVID-19-specific symptoms, he tested positive for SARS-CoV-2 before he died. Spike protein (S1) antigen-binding showed significant levels for immunoglobulin (Ig) G, while nucleocapsid IgG\/IgM was not elicited.<\/p>\n<p>Acute bronchopneumonia and tubular failure were assigned as the cause of death at autopsy; however, we did not observe any characteristic morphological features of COVID-19.<\/p>\n<p>Postmortem molecular mapping by real-time polymerase chain reaction revealed relevant SARS-CoV-2 cycle threshold values in all organs examined (oropharynx, olfactory mucosa, trachea, lungs, heart, kidney and cerebrum) except for the liver and olfactory bulb.<\/p>\n<p>These results might suggest that the first vaccination induces immunogenicity but not sterile immunity.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>First case of postmortem study in &#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":70041,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"","fifu_image_alt":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true},"categories":[26],"tags":[1224,930,1104,1225,1103],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/mackenmov.sunnyday.jp\/wordpress\/wp-content\/uploads\/2021\/07\/vac.jpg?fit=600%2C627&ssl=1","jetpack_sharing_enabled":true,"jetpack_likes_enabled":true,"_links":{"self":[{"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/posts\/70040"}],"collection":[{"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/comments?post=70040"}],"version-history":[{"count":0,"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/posts\/70040\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/media\/70041"}],"wp:attachment":[{"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/media?parent=70040"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/categories?post=70040"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mackenmov.sunnyday.jp\/wordpress\/wp-json\/wp\/v2\/tags?post=70040"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}